Data-Driven Conception

Breonna Slocum

5 min Read Breonna Slocum

Breonna Slocum

Data-Driven Conception

TTC the ParentData way

Breonna Slocum

5 min Read

Many of us in heterosexual relationships spend so much time trying to avoid pregnancy that when it comes to actively trying to conceive, it can feel like, “Okay, I stopped the birth control. Now what?” 

As a reproductive endocrinology and infertility physician fellow, I encounter this scenario often in the patients who come to see me. Stopping birth control is a great place to start, and for some, that may be all that is needed. But I like to plan, so if you’re like me and find yourself in the position to do so, there are a couple of other things you can do to maximize the chances of getting pregnant. 

Before we begin, I want to emphasize that if you don’t have time, the ability, or, frankly, the desire to do any of this, don’t panic! You won’t harm anything, and you can still have a healthy pregnancy. On the flip side, if you do all of this and still don’t end up pregnant, it’s not your (or your partner’s) fault. Infertility is very common, and there are many treatment options available if you need them. 

The other thing that is important to mention is that this article is specifically going to focus on things that people with ovaries in heterosexual relationships without the need for donor sperm or eggs can do to optimize the chances of success. If that is not you, some of the information here may still be helpful. However, there are other considerations for people who are in same-sex relationships or who need donor sperm or eggs, for a number of reasons. 

We’re going to talk about setting expectations, understanding your fertility window, and making a plan for how you’ll time sex. Let’s get started. 

Think about the long game

It’s a good idea to set realistic expectations for yourself and your partner from the beginning. Human reproduction is incredibly inefficient. Even for healthy heterosexual couples without infertility, it can take a year to conceive. This means that you can do everything right and it still may not happen even in the first few months of trying. But it can also happen right away, so be prepared for that possibility as well. 

It is really important, however, not to keep trying on your own for too long if there are signs that you may need help from a reproductive endocrinologist and fertility specialist. “Trying” doesn’t have to mean doing everything possible; it can just mean having regular unprotected sex. How long you should try before seeking help depends on your age. 

If you’re under 35 and you’ve been having unprotected sex with your partner for a year and haven’t gotten pregnant, you should see a specialist. If you are 35 years old or more, we suggest you seek help after trying for six months. If you are 40 years old or more, we suggest you see a specialist right away before you try to conceive. This is because the chances of conceiving at this age without help are lower, and treatment success goes down with age. 

You should also be seen right away if you have any condition that may make it more challenging for you to conceive without assistance, like polycystic ovary syndrome (PCOS) or endometriosis. You are more likely to need help conceiving with any of these conditions. 

Going into trying to conceive with the knowledge that it may take some time and that there are resources available to help you can be comforting. This is not only a physical journey but an emotional one as well, so talk to your partner about how you’ll navigate and support each other through this experience.

Understand your fertility window 

This may seem obvious, but step one is stopping your birth control if you’re taking any. Plan to stop your birth control about three to six months before you’re ready to start trying (use barrier contraception like condoms if you don’t want to become pregnant in this time frame). Depending on the type of birth control, your periods should restart right away, and you can use the few months before you’re ready to start trying to get a sense of your menstrual cycle. If your periods have not resumed by three months after stopping birth control, you should see a gynecologist, as this may be a sign of an underlying problem with ovulation.

Once you start trying, the main thing you can do to optimize your chances is having sex at the right time in your menstrual cycle. In any given menstrual cycle, fecundability — the probability of achieving a pregnancy — is possible during the five days before ovulation (see the graph below). This is because, once ovulated, an egg has about a 24-hour window to be fertilized. Ideally, sperm is already there waiting, so understanding your specific fertility window is key to optimizing your chances.

You experience your peak fecundability (i.e. when pregnancy is most likely to occur) when sex occurs within two days before ovulation. Historically, those trying for pregnancy were told to time sex for around this time. Unfortunately, that can be a pretty big mood killer (the pressure!). Luckily, sperm can survive in the reproductive tract for about five days. So a good alternative is to plan to have sex starting the week before you expect to ovulate. 

But wait, how do you know if you are ovulating? The easiest and most straightforward way is if you are having regular periods. What do we mean by regular? We mean having a period every 21 to 35 days. It is totally normal for the exact day that your period starts to fluctuate within a week or so, as long as you remain in the 21-to-35-day window. If you are not having regular periods, this is a concern and a reason to seek out help sooner.

While it is possible, it is very rare to have regular periods and not be ovulating, so many people with regular periods don’t need to do any specific testing to make sure. From here, estimating the day of ovulation involves some quick math; no matter how long your menstrual cycle is, the second half (after ovulation) is about 14 days. So you can subtract 14 from the day that you anticipate your period to get a rough idea of when ovulation will occur.  

What if you want to know exactly when you ovulate? There are a number of different ways to track ovulation, and one of the easiest is to use ovulation predictor kits. These are at-home urine tests (think pregnancy tests) that check for one of the hormones that surges with ovulation. Keep in mind that the exact date of ovulation will also likely fluctuate each cycle. You can purchase these online or at a local drugstore — there are many options available at different prices. 

A low-tech alternative is tracking your cervical mucus, which will typically go from a thick and sticky consistency to a clear, stretchy, and slippery consistency around the time of ovulation. There is also an increase in the amount of mucus, and it will typically peak two to three days before ovulation. This is by no means required for pregnancy to occur, so don’t be concerned if you don’t notice this change for you. Here is a great resource for how to perform this method.

Another low-tech option is checking your basal body temperature — the temperature your body is at rest. After ovulation, your basal body temperature will go up by fractions of a degree to a degree or two, so we’re talking about a very small increase. This is something that you’re going to want to take first thing when you get up in the morning, before you even get out of bed. It will give you retrospective data about when you ovulate; you’ll only find out after ovulation has occurred. So this is something you’ll want to do a few months ahead of time to get a general sense of when ovulation happens for you. 

Plan the timing of sex

A common misconception is that frequent ejaculation (aka having too much sex or masturbating too frequently) can decrease sperm quality. A retrospective study tackled this exact topic by examining about 10,000 semen samples from about 6,000 men. The study authors found that in men with normal semen quality, semen analysis parameters remained normal even with daily ejaculation. Surprisingly, the authors also found that for men with low sperm count, called oligospermia, daily ejaculation resulted in the highest sperm concentration and motility. While semen analysis parameters are not exactly the same as the capacity of the sperm to yield a healthy pregnancy, these data are helpful. 

Daily sex may be a tall ask. Another helpful study, this one a prospective study, of about 200 women who were trying to become pregnant, found that cycle fecundity — the probability of achieving a live birth — was similar with sex that occurred daily, every other day, and every three days within the fertility window. On the flip side, this study also showed that cycle fecundity was lowest when intercourse occurred only once during the fertility window, so don’t do that if you can help it. 

Does anything about the sex other than frequency matter? Sex position doesn’t matter at all, so do what you like! By the way, there’s no data to suggest any relationship between sex position and the infant’s sex. Unfortunately, there also isn’t any data to suggest that lying on your back after sex increases your chances of conceiving, though there is certainly no harm in doing so. 

The effects of specific lubricants on sperm have only been studied in a lab setting, and the data from these studies show that many of the commonly available lubricants (yes, even water-based ones) inhibit the ability of the sperm to move and slow them down. I cannot stress enough that this may not translate to how the sperm behaves in the vagina and the rest of the reproductive tract, so please take this finding with a huge grain of salt. Canola oil, mineral oil, and a commercially available lube called PreSeed have not been found to have this same effect, though again this may not reflect what goes on in your body. No matter what you decide, you should opt for whatever gives you the most enjoyable sex. 

Bottom line

  • It can take up to a year to get pregnant, even if you time everything “perfectly.” If you do not get pregnant by one year, it is not your or your partner’s fault, and you should see a reproductive endocrinologist and infertility specialist. 
  • Plan to stop birth control three to six months before you’re ready to start trying. Use this time to track your periods. If your periods do not resume by three months after stopping birth control, see a gynecologist. 
  • To optimize your chances of conceiving, you need to understand when you ovulate. There are multiple ways to track this, including estimating based on your cycle length, basal body temperature, cervical mucus, and ovulation predictor kits.
  • Once you are ready to start trying, aim to have sex every one to two days starting five days before you ovulate. 
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Is side sleeping important during pregnancy? Comment “Link” for a DM to an article on whether sleep position affects pregnancy outcomes.

Being pregnant makes you tired, and as time goes by, it gets increasingly hard to get comfortable. You were probably instructed to sleep on your side and not your back, but it turns out that advice is not based on very good data.

We now have much better data on this, and the bulk of the evidence seems to reject the link between sleep position and stillbirth or other negative outcomes. So go ahead and get some sleep however you are most comfortable. 💤

Sources:
📖 #ExpectingBetter pp. 160-163
📈 Robert M. Silver et al., “Prospective Evaluation of Maternal Sleep Position Through 30 Weeks of Gestation and Adverse Pregnancy Outcomes,” Obstetrics and Gynecology 134, no. 4 (2019): 667–76. 

#emilyoster #pregnancy #pregnancytips #sleepingposition #pregnantlife

Is side sleeping important during pregnancy? Comment “Link” for a DM to an article on whether sleep position affects pregnancy outcomes.

Being pregnant makes you tired, and as time goes by, it gets increasingly hard to get comfortable. You were probably instructed to sleep on your side and not your back, but it turns out that advice is not based on very good data.

We now have much better data on this, and the bulk of the evidence seems to reject the link between sleep position and stillbirth or other negative outcomes. So go ahead and get some sleep however you are most comfortable. 💤

Sources:
📖 #ExpectingBetter pp. 160-163
📈 Robert M. Silver et al., “Prospective Evaluation of Maternal Sleep Position Through 30 Weeks of Gestation and Adverse Pregnancy Outcomes,” Obstetrics and Gynecology 134, no. 4 (2019): 667–76.

#emilyoster #pregnancy #pregnancytips #sleepingposition #pregnantlife
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#tylenol #pregnancy #pregnancyhealth #pregnancytips #parentdata #emilyoster

Exciting news! We have new, high-quality data that says it’s safe to take Tylenol during pregnancy and there is no link between Tylenol exposure and neurodevelopmental issues in kids. Comment “Link” for a DM to an article exploring this groundbreaking study.

While doctors have long said Tylenol was safe, confusing studies, panic headlines, and even a lawsuit have continually stoked fears in parents. As a result, many pregnant women have chosen not to take it, even if it would help them.

This is why good data is so important! When we can trust the data, we can trust our choices. And this study shows there is no blame to be placed on pregnant women here. So if you have a migraine or fever, please take your Tylenol.

#tylenol #pregnancy #pregnancyhealth #pregnancytips #parentdata #emilyoster
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For this graph, researchers used a standardized measure of vocabulary size. Parents were given a survey and checked off all the words and sentences they have heard their child say.

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#cribsheet #emilyoster #parentdata #languagedevelopment #firstwords

How many words should kids say — and when? Comment “Link” for a DM to an article about language development!

For this graph, researchers used a standardized measure of vocabulary size. Parents were given a survey and checked off all the words and sentences they have heard their child say.

They found that the average child—the 50th percentile line—at 24 months has about 300 words. A child at the 10th percentile—near the bottom of the distribution—has only about 50 words. On the other end, a child at the 90th percentile has close to 600 words. One main takeaway from these graphs is the explosion of language after fourteen or sixteen months.

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#swimlessons #watersafety #kidsswimminglessons #poolsafety #emilyoster #parentdata

What age is best to start swim lessons? Comment “Link” for a DM to an article about water safety for children 💦

Summer is quickly approaching! You might be wondering if it’s the right time to have your kid start swim lessons. The AAP recommends starting between 1 and 4 years old. This is largely based on a randomized trial where young children were put into 8 or 12 weeks of swim lessons. They found that swimming ability and water safety reactions improve in both groups, and more so in the 12 weeks group.

Below this age range though, they are too young to actually learn how to swim. It’s fine to bring your baby into the pool (if you’re holding them) and they might like the water. But starting formal safety-oriented swim lessons before this age isn’t likely to be very helpful.

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 #emilyoster #parentdata #childnutrition #babynutrition #foodforkids

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Like with most things, moderation is key! Avoid very salty chips or olives or saltines with your infant. But if you’re doing baby-led weaning, it’s okay for them to share your lightly salted meals. Your baby does not need their own, unsalted, chicken if you’re making yourself a roast. Just skip the super salty stuff.

#emilyoster #parentdata #childnutrition #babynutrition #foodforkids
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What’s your experience with sleep training? Did you feel judged for your decision to do (or not do) it?

#sleeptraining #newparents #babysleep #emilyoster #parentdata

Is sleep training bad? Comment “Link” for a DM to an article breaking down the data on sleep training 😴

Among parenting topics, sleep training is one of the most divisive. Ultimately, it’s important to know that studies looking at the short- and long-term effects of sleep training show no evidence of harm. The data actually shows it can improve infant sleep and lower parental depression.

Even so, while sleep training can be a great option, it will not be for everyone. Just as people can feel judged for sleep training, they can feel judged for not doing it. Engaging in any parenting behavior because it’s what’s expected of you is not a good idea. You have to do what works best for your family! If that’s sleep training, make a plan and implement it. If not, that’s okay too.

What’s your experience with sleep training? Did you feel judged for your decision to do (or not do) it?

#sleeptraining #newparents #babysleep #emilyoster #parentdata
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Does your kid love to stall right before bedtime? 💤 Tell me more about their tactics in the comments below!

#funnytweets #bedtime #nightimeroutine #parentinghumor #parentingmemes

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#funnytweets #bedtime #nightimeroutine #parentinghumor #parentingmemes
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Having this realization, accepting it, reminding ourselves of it, can help us make the hard decisions and accurately weigh the risks and benefits of our choices.

#parentingquotes #decisionmaking #nosecretoptionc #parentingadvice #emilyoster #parentdata

Got a big decision to make? 🤔 Comment “Link” for a DM to read about my easy mantra for making hard choices.

When we face a complicated problem in pregnancy or parenting, and don’t like either option A or B, we often wait around for a secret third option to reveal itself. This magical thinking, as appealing as it is, gets in the way. We need a way to remind ourselves that we need to make an active choice, even if it is hard. The mantra I use for this: “There is no secret option C.”

Having this realization, accepting it, reminding ourselves of it, can help us make the hard decisions and accurately weigh the risks and benefits of our choices.

#parentingquotes #decisionmaking #nosecretoptionc #parentingadvice #emilyoster #parentdata
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Excuse the language, but I have such strong feelings about this subject! Sometimes, it feels like there’s no winning as a mother. People pressure you to breastfeed and, in the same breath, shame you for doing it in public. Which is it?!

So yes, they’re being completely unreasonable. You should be able to feed your baby in peace. What are some responses you can give to someone who tells you to cover up? Share in the comments below ⬇️

#breastfeeding #breastfeedinginpublic #breastfeedingmom #motherhood #emilyoster

Excuse the language, but I have such strong feelings about this subject! Sometimes, it feels like there’s no winning as a mother. People pressure you to breastfeed and, in the same breath, shame you for doing it in public. Which is it?!

So yes, they’re being completely unreasonable. You should be able to feed your baby in peace. What are some responses you can give to someone who tells you to cover up? Share in the comments below ⬇️

#breastfeeding #breastfeedinginpublic #breastfeedingmom #motherhood #emilyoster
...

Potty training can feel like a Mount Everest-size challenge, and sadly, our evidence-based guidance is poor. So, I created a survey to collate advice and feedback on success from about 6,000 participants.

How long does potty training take? We found that there is a strong basic pattern here: the later you wait to start, the shorter time it takes to potty train. On average, people who start at under 18 months report it takes them about 12 weeks for their child to be fully trained (using the toilet consistently for both peeing and pooping). For those who start between 3 and 3.5, it’s more like nine days. Keep in mind that for all of these age groups, there is a range of length of time from a few days to over a year. Sometimes parents are told that if you do it right, it only takes a few days. While that is true for some people, it is definitely not the norm.

If you’re in the throes of potty training, hang in there! 

#emilyoster #parentdata #pottytraining #pottytrainingtips #toddlerlife

Potty training can feel like a Mount Everest-size challenge, and sadly, our evidence-based guidance is poor. So, I created a survey to collate advice and feedback on success from about 6,000 participants.

How long does potty training take? We found that there is a strong basic pattern here: the later you wait to start, the shorter time it takes to potty train. On average, people who start at under 18 months report it takes them about 12 weeks for their child to be fully trained (using the toilet consistently for both peeing and pooping). For those who start between 3 and 3.5, it’s more like nine days. Keep in mind that for all of these age groups, there is a range of length of time from a few days to over a year. Sometimes parents are told that if you do it right, it only takes a few days. While that is true for some people, it is definitely not the norm.

If you’re in the throes of potty training, hang in there!

#emilyoster #parentdata #pottytraining #pottytrainingtips #toddlerlife
...

For children or adults with severe food allergies, they can be incredibly scary and restrictive. We may imagine that it’s easy to deal with a peanut allergy by, say, not eating peanut butter sandwiches. But for someone with a severe version of this allergy, they may never be able to go to a restaurant, for fear of a severe reaction to something in the air. Right now, there’s only one approved treatment for severe allergies like this and it’s limited to peanuts.

This is why the new medication Xolair is very exciting. It promises a second possible treatment avenue and one that works for other allergens. A new trail analyzed data from 177 children with severe food allergies. Two-thirds of the treatment group were able to tolerate the specified endpoint, versus just 7% of the placebo group. This is a very large treatment effect, and the authors found similarly large impacts on other allergens. 

There are some caveats: This treatment won’t work for everyone. (One-third of participants did not respond to it.) Additionally, this treatment is an injection given every two to four weeks, indefinitely. This may make it less palatable to children. 

Overall, even with caveats, this is life-changing news for many families!

#xolair #foodallergies #allergies #peanutallergy #emilyoster #parentdata

For children or adults with severe food allergies, they can be incredibly scary and restrictive. We may imagine that it’s easy to deal with a peanut allergy by, say, not eating peanut butter sandwiches. But for someone with a severe version of this allergy, they may never be able to go to a restaurant, for fear of a severe reaction to something in the air. Right now, there’s only one approved treatment for severe allergies like this and it’s limited to peanuts.

This is why the new medication Xolair is very exciting. It promises a second possible treatment avenue and one that works for other allergens. A new trail analyzed data from 177 children with severe food allergies. Two-thirds of the treatment group were able to tolerate the specified endpoint, versus just 7% of the placebo group. This is a very large treatment effect, and the authors found similarly large impacts on other allergens.

There are some caveats: This treatment won’t work for everyone. (One-third of participants did not respond to it.) Additionally, this treatment is an injection given every two to four weeks, indefinitely. This may make it less palatable to children.

Overall, even with caveats, this is life-changing news for many families!

#xolair #foodallergies #allergies #peanutallergy #emilyoster #parentdata
...

If you have a fever during pregnancy, you should take Tylenol, both because it will make you feel better and because of concerns about fever in pregnancy (although these are also overstated).

The evidence that suggests risks to Tylenol focuses largely on more extensive exposure — say, taking it for more than 28 days during pregnancy. There is no credible evidence, even correlational, to suggest that taking it occasionally for a fever or headache would be an issue.

People take Tylenol for a reason. For many people, the choice may be between debilitating weekly migraines and regular Tylenol usage. The impacts studies suggest are very small. In making this decision, we should weigh the real, known benefit against the suggestion of this possible risk. Perhaps not everyone will come out at the same place on this, but it is crucial we give people the tools to make the choice for themselves.

#emilyoster #parentdata #tylenol #pregnancy #pregnancytips

If you have a fever during pregnancy, you should take Tylenol, both because it will make you feel better and because of concerns about fever in pregnancy (although these are also overstated).

The evidence that suggests risks to Tylenol focuses largely on more extensive exposure — say, taking it for more than 28 days during pregnancy. There is no credible evidence, even correlational, to suggest that taking it occasionally for a fever or headache would be an issue.

People take Tylenol for a reason. For many people, the choice may be between debilitating weekly migraines and regular Tylenol usage. The impacts studies suggest are very small. In making this decision, we should weigh the real, known benefit against the suggestion of this possible risk. Perhaps not everyone will come out at the same place on this, but it is crucial we give people the tools to make the choice for themselves.

#emilyoster #parentdata #tylenol #pregnancy #pregnancytips
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Parenting trends are like Cabbage Patch Kids: they’re usually only popular because a bunch of people are using them! Most of the time, these trends are not based on new scientific research, and even if they are, that new research doesn’t reflect all of what we’ve studied before.

In the future, before hopping onto the latest trend, check the data first. Unlike Cabbage Patch Kids, parenting trends can add a lot of unnecessary stress and challenges to your plate. What’s a recent trend that you’ve been wondering about?

#parentdata #emilyoster #parentingtips #parentingadvice #parentinghacks

Parenting trends are like Cabbage Patch Kids: they’re usually only popular because a bunch of people are using them! Most of the time, these trends are not based on new scientific research, and even if they are, that new research doesn’t reflect all of what we’ve studied before.

In the future, before hopping onto the latest trend, check the data first. Unlike Cabbage Patch Kids, parenting trends can add a lot of unnecessary stress and challenges to your plate. What’s a recent trend that you’ve been wondering about?

#parentdata #emilyoster #parentingtips #parentingadvice #parentinghacks
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